M. lignano Neoblast Screen 2016.
Mlig455 transcriptome version. Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano. (2016) Grudniewska M*, Mouton S*, Simanov S, Beltman F, Grelling M, de Mulder K, Arindrarto W, Weissert P, van der Elst S, Berezikov E. eLife 2016;5:e20607. Home Download

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Found 399 results for log2(CutG2M/CutG1) <= -1 and fdr <= 0.05. Showing entries 1-20.

Graph Cluster Transcripts Mean logCPM Classification Smed/Human type Human gene Annotation
1. MligTC455_24832 Mlig455_026454 4.36 Xins GM2A Mlig455_026454 {REF} {Length: 1032} {Pfam: ML domain [PF02221.17, score=45.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=3e-11]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=64.3, Expect=3e-12]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [RH, Score=89.4, Expect=4e-22]} {RNA1509_8277} {RNA1310_42438} {RNA815_22343} {SMEDTYPE: Xins [raj_facs_types]}
2. MligTC455_28410 Mlig455_059490 4.1 WSCD2 Mlig455_059490 {REF} {Length: 885} {Pfam: WSC domain [PF01822.21, score=91.9]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=53.5, Expect=8e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=52.4, Expect=1e-07]} {Dmel: FBgn0046685, Wsck, [Score=47.8, Expect=3e-06]} {RNA1509_1090, RNA1509_34744, RNA1509_74} {RNA1310_36278, RNA1509_1090, RNA1509_34744} {RNA1509_1090, RNA1509_34744, RNA815_20163.1}
3. MligTC455_41645 Mlig455_056534 3.84 SELENBP1 Mlig455_056534 {REF} {Length: 2301} {Pfam: 56kDa selenium binding protein (SBP56) [PF05694.13, score=668.6]} {Human: ENSG00000143416, SELENBP1, selenium binding protein 1, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000068874, Selenbp1, selenium binding protein 1, [RH, Score=598, Expect=0.0]; ENSMUSG00000068877, Selenbp2, selenium binding protein 2, [RH, Score=589, Expect=0.0]} {Dmel: FBgn0038115, CG7966, [RH, Score=490, Expect=6e-171]} {Celegans: WBGene00012538, Y37A1B.5, [RH, Score=524, Expect=0.0]} {RNA1509_122, RNA1509_1455} {RNA1310_13697, RNA1509_122, RNA1509_1455} {RNA1509_122, RNA1509_1455, RNA815_5156}
4. MligTC455_32318 Mlig455_016815 3.49 Gut; Xins; Sexual_biased CTSA Mlig455_016815 {REF} {Length: 2775} {Pfam: Serine carboxypeptidase [PF00450.24, score=407.0]} {Human: ENSG00000064601, CTSA, cathepsin A, [RH, Score=420, Expect=9e-143]} {Mouse: ENSMUSG00000017760, Ctsa, cathepsin A, [RH, Score=428, Expect=6e-146]} {Dmel: FBgn0038738, CG4572, [Score=108, Expect=3e-25]} {Celegans: WBGene00019605, ctsa-1, Uncharacterized serine carboxypeptidase ctsa-1, [RH, Score=344, Expect=1e-113]} {Smed: dd_Smed_v6_785_0_1, dd_Smed_v6_785_0_1, [RH, Score=392, Expect=3e-132]} {RNA1509_366} {RNA1310_10272.1} {RNA815_3612.1} {SMEDTYPE: Gut [dd_Smed_v6_785_0_1, cathepsin A (CTSA)]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.626805.0]}
5. MligTC455_16924 Mlig455_038673 3.33 KREMEN2 Mlig455_038673 {REF} {Length: 1868} {Pfam: WSC domain [PF01822.21, score=94.9]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=47.8, Expect=7e-06]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=46.6, Expect=1e-05]} {RNA1509_2263, RNA1509_2602, RNA1509_627} {RNA1310_28866, RNA1509_2263, RNA1509_2602, RNA1509_627} {RNA1509_2263, RNA1509_2602, RNA1509_627, RNA815_15018.1}
6. MligTC455_27345 Mlig455_014663 3.32 TNN Mlig455_014663 {REF} {Length: 1341} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=95.8]} {Human: ENSG00000120332, TNN, tenascin N, [Score=88.6, Expect=2e-18]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=87.0, Expect=5e-18]} {Dmel: FBgn0051832, CG31832, [Score=81.6, Expect=9e-18]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=60.1, Expect=9e-10]} {RNA1509_14450, RNA1509_21789, RNA1509_24312, RNA1509_34168, RNA1509_460, RNA1509_4614} {RNA1310_30528, RNA1509_14450, RNA1509_21789, RNA1509_24312, RNA1509_34168, RNA1509_460, RNA1509_4614} {RNA1509_14450, RNA1509_21789, RNA1509_24312, RNA1509_34168, RNA1509_460, RNA1509_4614, RNA815_9549.3}
7. MligTC455_28758 Mlig455_053395 3.26 X1; Sexual_biased UBE2O Mlig455_053395 {REF} {Length: 14273} {TRANSSPLICED} {Human: ENSG00000175931, UBE2O, ubiquitin conjugating enzyme E2 O, [Score=91.7, Expect=4e-18]} {Mouse: ENSMUSG00000020802, Ube2o, ubiquitin-conjugating enzyme E2O, [Score=92.8, Expect=1e-18]} {Dmel: FBgn0027512, CG10254, [Score=72.4, Expect=2e-12]} {Smed: dd_Smed_v6_9319_0_1, dd_Smed_v6_9319_0_1, [Score=105, Expect=7e-23]} {RNA1509_28643, RNA1509_5756} {RNA1310_576.1, RNA1509_5756} {RNA1509_5756, RNA815_1671.1} {SMEDTYPE: X1 [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.431168.0]}
8. MligTC455_49860 Mlig455_034959 3.25 Xins CTSS Mlig455_034959 {REF} {Length: 3986} {Pfam: Papain family cysteine protease [PF00112.25, score=293.3]; Cathepsin propeptide inhibitor domain (I29) [PF08246.14, score=46.6]; Peptidase C1-like family [PF03051.17, score=19.4]} {Human: ENSG00000163131, CTSS, cathepsin S, [RH, Score=323, Expect=5e-109]} {Mouse: ENSMUSG00000038642, Ctss, cathepsin S, [RH, Score=310, Expect=6e-104]} {Dmel: FBgn0013770, Cp1, Cysteine proteinase-1, [Score=364, Expect=3e-125]} {Celegans: WBGene00000776, cpl-1, CathePsin L family, [RH, Score=335, Expect=2e-114]} {Smed: dd_Smed_v6_267_0_1, dd_Smed_v6_267_0_1, [Score=382, Expect=1e-132]} {RNA1509_17461, RNA1509_2857, RNA1509_35872, RNA1509_52415} {RNA1310_37445.1, RNA1509_17461, RNA1509_2857, RNA1509_35872, RNA1509_52415} {RNA1509_17461, RNA1509_2857, RNA1509_35872, RNA1509_52415, RNA815_12006} {SMEDTYPE: Xins [raj_facs_types]}
9. MligTC455_42914 Mlig455_042934 3.23 XDH Mlig455_042934 {REF} {Length: 4720} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=413.8]; [2Fe-2S] binding domain [PF01799.22, score=94.9]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=87.5]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=79.5]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=71.3]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=504, Expect=8e-156]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=505, Expect=3e-156]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=488, Expect=6e-150]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [RH, Score=754, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=547, Expect=6e-172]} {RNA1509_1237, RNA1509_27452, RNA1509_40864, RNA1509_55235, RNA1509_57977} {RNA1310_1253.1, RNA1509_1237, RNA1509_27452, RNA1509_40864, RNA1509_55235, RNA1509_57977} {RNA1509_1237, RNA1509_27452, RNA1509_40864, RNA1509_55235, RNA1509_57977, RNA815_469.1}
10. MligTC455_47421 Mlig455_013463 3.2 Mlig455_013463 {REF} {Length: 3134} {RNA1509_1364, RNA1509_21539, RNA1509_34329} {RNA1310_5108, RNA1509_1364, RNA1509_21539, RNA1509_34329} {RNA1509_1364, RNA1509_21539, RNA1509_34329, RNA815_1592.1}
11. MligTC455_22309 Mlig455_009649 3.19 Mlig455_009649 {REF} {Length: 1980} {RNA1509_2826, RNA1509_42163, RNA1509_466, RNA1509_6596, RNA1509_9666} {RNA1310_10184.1, RNA1509_2826, RNA1509_42163, RNA1509_466, RNA1509_6596, RNA1509_9666} {RNA1509_2826, RNA1509_42163, RNA1509_466, RNA1509_6596, RNA1509_9666, RNA815_3434}
12. MligTC455_42602 Mlig455_020003 3.19 Muscle; Xins; Asexual_biased Mlig455_020003 {REF} {Length: 2187} {Pfam: PLAC8 family [PF04749.19, score=78.5]} {Smed: dd_Smed_v6_477_0_1, dd_Smed_v6_477_0_1, [RH, Score=129, Expect=2e-40]} {RNA1509_10477, RNA1509_10789, RNA1509_11416, RNA1509_13483, RNA1509_13946, RNA1509_14839, RNA1509_16689, RNA1509_1735, RNA1509_21370, RNA1509_24499, RNA1509_29492, RNA1509_41089, RNA1509_7129} {RNA1310_19971.1, RNA1509_10477, RNA1509_10789, RNA1509_11416, RNA1509_13483, RNA1509_13946, RNA1509_14839, RNA1509_16689, RNA1509_1735, RNA1509_21370, RNA1509_24499, RNA1509_29492, RNA1509_41089, RNA1509_7129} {RNA1509_10477, RNA1509_10789, RNA1509_11416, RNA1509_13483, RNA1509_13946, RNA1509_14839, RNA1509_16689, RNA1509_1735, RNA1509_21370, RNA1509_24499, RNA1509_29492, RNA1509_41089, RNA1509_7129, RNA815_8854.1} {SMEDTYPE: Muscle [dd_Smed_v6_477_0_1, placenta-specific 8 (PLAC8)]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Asexual_biased [CUFF.521209.0]}
13. MligTC455_28759 Mlig455_015450 3.14 Mlig455_015450 {REF} {Length: 337} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_18729} {RNA1310_68532} {RNA815_18679}
14. MligTC455_38778 Mlig455_054825, Mlig455_054817 3.11

Mlig455_054825 {REF} {Length: 1268} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=34.8]} {Smed: dd_Smed_v6_5756_0_1, dd_Smed_v6_5756_0_1, [RH, Score=48.1, Expect=1e-07]} {RNA1509_1053, RNA1509_1110, RNA1509_1758} {RNA1310_34072.1, RNA1509_1053, RNA1509_1110, RNA1509_1758} {RNA1509_1053, RNA1509_1110, RNA1509_1758, RNA815_14544}

Mlig455_054817 {REF} {Length: 990} {TRANSSPLICED} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=34.3]} {Smed: dd_Smed_v6_5756_0_1, dd_Smed_v6_5756_0_1, [RH, Score=47.8, Expect=2e-07]} {RNA1509_1053} {RNA1310_34072.1} {RNA815_14544}
15. MligTC455_27720 Mlig455_041398 3.11 Gamma neoblasts; Xins ACTG1 Mlig455_041398 {REF} {Length: 1534} {Pfam: Actin [PF00022.21, score=419.7]} {Human: ENSG00000184009, ACTG1, actin gamma 1, [Score=622, Expect=0.0]; ENSG00000075624, ACTB, actin beta, [Score=621, Expect=0.0]; ENSG00000159251, ACTC1, actin, alpha, cardiac muscle 1, [Score=604, Expect=0.0]; ENSG00000107796, ACTA2, actin, alpha 2, smooth muscle, aorta, [Score=603, Expect=0.0]; ENSG00000163017, ACTG2, actin, gamma 2, smooth muscle, enteric, [Score=603, Expect=0.0]; ENSG00000169067, ACTBL2, actin, beta like 2, [Score=598, Expect=0.0]; ENSG00000143632, ACTA1, actin, alpha 1, skeletal muscle, [Score=598, Expect=0.0]} {Mouse: ENSMUSG00000062825, Actg1, actin, gamma, cytoplasmic 1, [Score=622, Expect=0.0]; ENSMUSG00000029580, Actb, actin, beta, [Score=621, Expect=0.0]; ENSMUSG00000068614, Actc1, actin, alpha, cardiac muscle 1, [Score=604, Expect=0.0]; ENSMUSG00000059430, Actg2, actin, gamma 2, smooth muscle, enteric, [Score=603, Expect=0.0]; ENSMUSG00000035783, Acta2, actin, alpha 2, smooth muscle, aorta, [Score=603, Expect=0.0]; ENSMUSG00000055194, Actbl2, actin, beta-like 2, [Score=600, Expect=0.0]; ENSMUSG00000031972, Acta1, actin, alpha 1, skeletal muscle, [Score=598, Expect=0.0]} {Dmel: FBgn0000046, Act87E, Actin 87E, [Score=621, Expect=0.0]} {Celegans: WBGene00000067, act-5, ACTin, [Score=604, Expect=0.0]} {Smed: dd_Smed_v6_3_0_1, dd_Smed_v6_3_0_1, [Score=626, Expect=0.0]} {RNA1509_13476, RNA1509_17616, RNA1509_51084} {RNA1310_20267.1, RNA1509_13476, RNA1509_17616} {RNA1509_13476, RNA1509_17616, RNA815_10170} {SMEDTYPE: Gamma neoblasts [dd_Smed_v6_3_0_1, actin, beta (ACTB)]} {SMEDTYPE: Xins [raj_facs_types]}
16. MligTC455_46392 Mlig455_048871 3.08 Muscle; Xins; Sexual_biased; self-renewal; repression CNN3 Mlig455_048871 {REF} {Length: 1248} {Pfam: Calponin homology (CH) domain [PF00307.33, score=81.5]; Calponin family repeat [PF00402.20, score=42.8]} {Human: ENSG00000117519, CNN3, calponin 3, [Score=134, Expect=6e-38]; ENSG00000144834, TAGLN3, transgelin 3, [Score=134, Expect=3e-39]; ENSG00000158710, TAGLN2, transgelin 2, [Score=132, Expect=2e-38]; ENSG00000064666, CNN2, calponin 2, [Score=130, Expect=1e-36]} {Mouse: ENSMUSG00000053931, Cnn3, calponin 3, acidic, [Score=134, Expect=5e-38]; ENSMUSG00000022658, Tagln3, transgelin 3, [Score=134, Expect=2e-39]; ENSMUSG00000004665, Cnn2, calponin 2, [Score=132, Expect=1e-37]; ENSMUSG00000026547, Tagln2, transgelin 2, [Score=131, Expect=2e-38]; ENSMUSG00000001349, Cnn1, calponin 1, [Score=128, Expect=9e-37]} {Dmel: FBgn0002789, Mp20, Muscle protein 20, [RH, Score=201, Expect=4e-66]} {Celegans: WBGene00000777, cpn-1, CPN-1; CalPoNin, [Score=127, Expect=5e-37]} {Smed: dd_Smed_v6_1512_0_1, dd_Smed_v6_1512_0_1, [RH, Score=284, Expect=5e-99]} {RNA1509_555} {RNA1310_32900.2} {RNA815_14879} {SMEDTYPE: Muscle [dd_Smed_v6_1512_0_1, transgelin 3 (TAGLN3)]} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Sexual_biased [CUFF.590805.0]} {SMEDTYPE: self-renewal [16]} {SMEDTYPE: repression [10]}
17. MligTC455_50277 Mlig455_056261, Mlig455_036476 3.04 Xins; Asexual_biased TNNI2

Mlig455_056261 {REF} {Length: 1736} {Pfam: Troponin [PF00992.22, score=109.0]} {Human: ENSG00000130598, TNNI2, troponin I2, fast skeletal type, [RH, Score=53.9, Expect=4e-08]; ENSG00000159173, TNNI1, troponin I1, slow skeletal type, [RH, Score=51.6, Expect=2e-07]} {Mouse: ENSMUSG00000031097, Tnni2, troponin I, skeletal, fast 2, [RH, Score=47.8, Expect=3e-06]} {Dmel: FBgn0283471, wupA, wings up A, [RH, Score=106, Expect=5e-27]} {Celegans: WBGene00006586, tni-4, Troponin I 4, [RH, Score=107, Expect=8e-28]} {Smed: dd_Smed_v6_7974_0_1, dd_Smed_v6_7974_0_1, [RH, Score=181, Expect=8e-55]} {RNA1509_3188} {RNA1310_4012} {RNA815_7139.1} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Asexual_biased [CUFF.453293.0]}

Mlig455_036476 {REF} {Length: 2140} {Pfam: Troponin [PF00992.22, score=109.0]} {Human: ENSG00000130598, TNNI2, troponin I2, fast skeletal type, [RH, Score=53.9, Expect=4e-08]; ENSG00000159173, TNNI1, troponin I1, slow skeletal type, [RH, Score=51.6, Expect=2e-07]} {Mouse: ENSMUSG00000031097, Tnni2, troponin I, skeletal, fast 2, [RH, Score=47.8, Expect=3e-06]} {Dmel: FBgn0283471, wupA, wings up A, [RH, Score=106, Expect=5e-27]} {Celegans: WBGene00006586, tni-4, Troponin I 4, [RH, Score=107, Expect=8e-28]} {Smed: dd_Smed_v6_7974_0_1, dd_Smed_v6_7974_0_1, [RH, Score=181, Expect=8e-55]} {RNA1509_3188, RNA1509_59846} {RNA1310_4012, RNA1509_59846} {RNA1509_59846, RNA815_7139.2} {SMEDTYPE: Xins [raj_facs_types]} {SMEDTYPE: Asexual_biased [CUFF.453293.0]}
18. MligTC455_32563 Mlig455_021721 3.04 Mlig455_021721 {REF} {Length: 1079} {RNA1509_570} {RNA1310_40828} {RNA815_5866.1}
19. MligTC455_45317 Mlig455_037806, Mlig455_037737 3.03

Mlig455_037806 {REF} {Length: 2442} {RNA1509_20048, RNA1509_26966, RNA1509_8140, RNA1509_9976} {RNA1310_9473.1, RNA1509_20048, RNA1509_26966, RNA1509_8140} {RNA1509_20048, RNA1509_26966, RNA1509_8140, RNA815_4341.1}

Mlig455_037737 {REF} {Length: 2604} {RNA1509_1424, RNA1509_53437, RNA1509_9976} {RNA1310_9473.1, RNA1509_1424, RNA1509_53437, RNA1509_9976} {RNA1509_1424, RNA1509_53437, RNA1509_9976, RNA815_4341.1}
20. MligTC455_37079 Mlig455_030956 3.03 Mlig455_030956 {REF} {Length: 6079} {Pfam: CUB domain [PF00431.22, score=21.4]} {RNA1509_19646, RNA1509_30863, RNA1509_51147, RNA1509_52744, RNA1509_57527, RNA1509_705} {RNA1310_578, RNA1509_19646, RNA1509_30863, RNA1509_52744, RNA1509_57527, RNA1509_705} {RNA1509_19646, RNA1509_30863, RNA1509_52744, RNA1509_57527, RNA1509_705, RNA815_71.1}
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